You've probably heard a widespread myth about the chemical dopamine, which is thought to be responsible for ensuring that cannabis brings exhilarating, uplifting and healthier effects. This claim has been repeatedly made in the media over the past few decades. Its main message is that THC stimulates the production of increased amounts of dopamine, which makes marijuana lovers feel good about themselves.
Where did the media get this information from? For over four decades, drug scientists have used the unifying theory that almost all addictive substances in humans fill the limbic system of the brain with dopamine.
This is how the representatives of the National Institute for Drug Abuse Control (NIDA), located in the United States, spoke about it:
"THC, acting through cannabinoid receptors, also activates the brain's reward system, which includes areas that regulate responses to healthy, pleasant behavior. These include sex and eating. Like most of the psychoactive substances in cannabis, THC stimulates the neurons in the brain's reward system to produce high levels of dopamine, far exceeding those that occur when you respond to a natural stimulus. This flow of dopamine produces a sublime effect that all recreational marijuana advocates seek to experience.
NIDA's position is not intentionally deceiving. By acting on endocannabinoid receptors, THC affects the human brain, but the release of large amounts of dopamine is unlikely. Where does this information come from? Unlike the early animal studies that underpin NIDA findings and the opinions of many narcologists, data from human studies do not support this.
In fact, numerous studies on humans show that, at best, cannabis use results in only a slight increase in dopamine, which is in no way comparable to that reported in the media. However, similar studies
on cocaine and amphetamines clearly indicate high levels of dopamine secretion.
In 2015, researchers at King's College London conducted a systematic review of each of the 25 published research results. They found that there was little direct evidence that cannabis https://gg4.store/product-category/indica/
caused high levels of dopamine to be released or changed the way dopamine receptors work in healthy volunteers.